Macromolecule developed by IBM could fight multiple viruses at once.

Finding a cure for viruses like Ebola, Zika, or even the flu is a challenging task. Viruses are vastly different from one another, and even the same strain of a virus can mutate and change–that’s why doctors give out a different flu vaccine each year. But a group of researchers at IBM and the Institute of Bioengineering and Nanotechnology in Singapore sought to understand what makes all viruses alike. Using that knowledge, they’ve come up with a macromolecule that may have the potential to treat multiple types of viruses and prevent them from infecting us. The work was published recently in the journal Macromolecules.

read the full article.. www.popsci.com/macromolecule-developed-by-ibm-could-fight-multiple-viruses-at-once


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Ways To Slow Aging.

An increasingly utilitarian body of research suggests that we have some control over the rate at which we age. Although genetics influences aging, environment may be a more important determinant (up to 2/3) of longevity. Food, temperature and physical activity, the primary environmental factors, affect healthspan in most animal models, including humans.

read full article.. www.huffingtonpost.com/paul-spector-md/not-so-fast-3-ways-to-slo_b_12661378.html


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Natural compound reduces signs of aging in healthy mice.

Much of human health hinges on how well the body manufactures and uses energy. For reasons that remain unclear, cells’ ability to produce energy declines with age, prompting scientists to suspect that the steady loss of efficiency in the body’s energy supply chain is a key driver of the aging process. Now, scientists have shown that supplementing healthy mice with a natural compound called NMN can compensate for this loss of energy production, reducing typical signs of aging such as gradual weight gain, loss of insulin sensitivity and declines in physical activity.

read the full article.. www.sciencedaily.com/releases/2016/10/161027122047.htm


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Expanding Sources.

This week I had to triple the list of medical news sites to review daily as there have been times when for a week nothing relevant to my research showed up. Thus nothing relevant were to post in my blog neither, apart of my own thoughts, opinions and longer writings.

Many of the medical websites repeat each other over and over, in different words and different headlines. I avoid repeating on the YE blog — if I know it has been posted and new ‘discovery’ makes headlines on the medical news websites again, sometimes many months later, then I simply ignore the news. Hopefully more diverse material can be posted now, related to the topic. I spend several hours a day for going through all the material out there, so if nothing new is posted on the YE blog it’s simply because there isn’t anything worth posting here. I keep the blog as close to the subject as possible, except on the side also promoting my own books, some of which may be a bit out of the topic of longevity and life/youth extension. Books are my only source of income right now – several more to come.. who knows when though, there’s a lot of work to be done yet.

Obviously there’s a limit to how much I can do and how much new published material to go through to select for posting on the blog, thus always do your own reasearch as well to find the news I have missed.


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The book “Seeming Reality” has now a price – no more for free.

You can now buy the book Seeming Reality for EUR 1.99 or in other currencies of the related value..

available on sellfy.com/youthextension

The book is about philosophy and psychology of thinking, including some legends of martial arts with the way of thinking the masters were applying to different situations in life — a useful teaching to take control of your mind. The book is based on my studies (beginning since nine years of age) and practice for over fifteen years prior to writing the book, almost twenty years ago now. It was written for the students of my private school of martial arts. The content is unchanged — the book is now with corrected errors of translation. I didn’t speak English when it was translated, now I decided to take a better look at the English translation which I’ve done couple of times already.. last time in 2006, now once again.

The book Advanced Handwriting Cryptography / Free Examples also available.


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Women nearing equality with men – in alcohol consumption.

Women have all but caught up with men at knocking back alcohol, a global study of drinking habits shows. The analysis of 4 million people, born between 1891 and 2001, showed that men used to be far more likely to drink and have resulting health problems. But the current generation have pretty much closed the gap, the BMJ Open report says.

/…/ The team at the University of New South Wales, in Australia, analysed data from people all over the world – although it was massively skewed towards North America and Europe.

read the article.. www.bbc.co.uk/news/health-37751132


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Don’t believe your eyes.

A research team of Bard Ermentrout from the University of Pittsburgh’s Kenneth P. Dietrich School of Arts and Sciences and Joel Pearson from The University of New South Wales in Australia have come up with a way to create hallucinations that could make them easier to be studied objectively, potentially leading to new treatment methods.

read the article.. www.sciencedaily.com/releases/2016/10/161024104223.htm


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If you wish to live long and healthy do your own research as well, don’t just believe all the science news.

Why should one do his/her own research. Lets look into the dangers of not doing it. What is fraud as such? It is deliberate trickery intended to gain an advantage. In that sense any woman who puts on makeup is committing fraud to gain advantage over competing women by hiding her real face as it is. No wonder men get disappointed in women pretty fast after realizing the trickery, which definitely isn’t limited with makup on face only. Men as well use trickery for the reality to appear different from what it really is, for their advantage. As it is the very human nature to use fraud in everyday life then it is no wonder that many scientists are conducting research on hidden fraudulent data, to gain personal advantage. This applies also to research in the fields of immortality and longevity, but in this field we cannot afford to take wrong decisions — you can only get the whole picture on possible healthy longevity right once. Thus in this field everyone must continuously keep an eye on developments in related sciences, learn as much as possible, and come to personal conclusions avoiding making decisions on fraudulent data. You cannot rely just on what some scientists have said or written. You must be educated enough to make your own decisions how to use research data in your life, to truly achieve an incredible longevity with excellent health.


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Creating ‘God’ – if we can do it, it may have been done before.

Once you realize that there’s a possibility to become immortal tapping into the very framework of human body on genetical/molecular/atomic level, and merging with technology, you realize that there’s a possibility for the existence of god — other entities may have achieved immortality in the past and are hanging now around watching the ‘lower’ entities who are created “in the image of god”. Ray Kurzweil has said: “Does God Exist? Well I would say, not yet.” It was said in the technological sense, that Artificial Intelligence would merge with the whole human race connecting all together and expanding further into the universe, creating universal mind. It implies the possibility that it has already been achieved before us, humans, and is in existence already.


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The new scanners that can really get inside your head.

New visions of the brain and body’s detailed operations will be unveiled by a suite of medical scanners being opened this week. The newly refurbished Wolfson Brain Imaging Centre in the University of Cambridge has been equipped with some of the world’s most powerful magnetic resonance imaging (MRI) and positron emission tomography (PET) scanners and will give its researchers unprecedented power to make images.

read the full article.. www.theguardian.com/science/2016/oct/23/powerful-brain-scanners-cambridge-neuroscience


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Seeming Reality, a book on philosophy and psychology of thinking..

Seeming Reality

Now a book on psychology of thinking available on sellfy.com/youthextension ..that’s the English version of my book which I wrote almost 20 years ago (1997), to my students of martial arts. Soon I will put a price tag on it (perhaps after few days), so use the opportunity to download the book for free.. sellfy.com/p/WTto/


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First glimpse of end-of chromosome repair in real time.

Maintaining the ends of chromosomes, called telomeres, allows cells to continuously divide and achieve immortality. “Telomeres are much like the plastic cap on the ends of shoelaces—they keep the ends of DNA from fraying,” said Roger Greenberg, MD, PhD, an associate professor of Cancer Biology in the Perelman School of Medicine at the University of Pennsylvania. In a new study published this week in Nature, senior author Greenberg and colleagues have developed a first-of-its- kind system to observe repair to broken DNA in newly synthesized telomeres, an effort which has implications for designing new cancer drugs.

read the full article.. medicalxpress.com/news/2016-10-glimpse-end-of-chromosome-real.html


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An opinion about coffee (‘taofe’ in Tahitian).

Recently I have read in medical literature some articles about benefits of coffee approaching the topic of the benefit from different angles, which by my gut feeling are planted there with the backing of coffee industry. The most recent article which didn’t feel right was about benefits of coffee for reducing effects of alcohol — Coffee, Genetics May Block Hepatitis in Heavy Drinkers www.medpagetoday.com/MeetingCoverage/ACG/60853 — the results were based on patients’ subjective reporting about the use of coffee, which data is easy to manipulate and impossible to verify.

My personal alcohol consumption is almost zero — I drink alcohol socially in very rare occasions, last time over half a year ago when on a business trip in France, staying at friends. I don’t need that presumed ‘benefit’ of coffee, but that article may subconsciously trigger the need to drink coffee in many, after having a booze. Looks like the target group to influence was carefully selected, considering the state of diminished critical thinking, relaxed attitude towards consequences and urgent need to reduce bad effect of alcohol after becoming half sober. The overall psychological impact of the above mentioned article is huge considering also the mechanism of justification for harming actions against oneself, à la “if I drink coffee after alcohol it will eliminate the harm”. But the mathematics of two negatives giving positive (which may also have been the psychological intent of the planted article, to tap into subconscious mind) isn’t working on human body.

Apart of short time pleasure the coffee isn’t doing much good to your body. Recent scientific research shows that you’ll be better off dropping the habit of coffee drinking, for several reasons.. so, the recent media attack by positive articles looks like counteroffensive to me. But I must emphasize that this is my personal opinion, a gut feeling based on what I have learned.. I cannot prove it, or rather I have no time to do a deeper research into that particular issue who exactly was backing the studies that showed the benefits of coffee. The results of the studies simply didn’t make sense based on what I know about coffee.

Personally I do drink coffee regardless of all what I know about how it affects body, but as in all the other senses I’m having a very healthy lifestyle coffee doesn’t become “yet another” affecting weight in overall pressure on my physiology. It is neutralized easily with all the other positive factors.. thus I am allowed to have that short time pleasure, keeping in mind that as soon as I feel a decline in health the first thing I do to regain health will be eliminating coffee from consumption, if that can be the cause of my sudden health problem. So far I’m doing great.

Drinking coffee is probably the only bad habit I have (can’t think of any other).. and perhaps not coincidentally the easy access domain to the YE blog taofe.com comes from the word ‘coffee’ — ‘taofe’ means coffee in Tahitian. (I lived/worked in Tahiti for a while and chose that domain name while I was there). Thus you can’t blame me in being biased: I like coffee but I keep myself informed about the downside of its consumption, ready to quit as soon as the downside outweighs the moments of small pleasure.


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Migraines could be caused by gut bacteria.

Migraine sufferers have a different mix of gut bacteria that could make them more sensitive to certain foods, scientists have found. The study offers a potential explanation for why some people are more susceptible to debilitating headaches and why some foods appear to act as triggers for migraines.

Nitrates, found in foods such as processed meats and green leafy vegetables and in certain medicines, can be reduced to nitrites by bacteria found in the mouth. When circulating in the blood, these nitrites can then be converted to nitric oxide under certain conditions. Nitric oxide can aid cardiovascular health by improving blood flow and reducing blood pressure. However, roughly four in five cardiac patients who take nitrate-containing drugs for chest pain or congestive heart failure report severe headaches as a side effect.

read the articles..
theguardian.com/science/2016/oct/18/migraines-could-be-caused-by-gut-bacteria-nitrates-food-trigger-study-suggests
medicalxpress.com/news/2016-10-migraine-nitrate-reducing-microbes-mouths.html


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Depression’s physical source discovered.

Understanding of the physical root of depression has been advanced, thanks to research by the University of Warwick, UK, and Fudan University, China. The study shows that depression affects the part of the brain which is implicated in non-reward—the lateral orbitofrontal cortex—so that sufferers of the disease feel a sense of loss and disappointment associated with not receiving rewards. Depression is also associated with reduced connectivity between the reward brain area in the medial orbitofrontal cortex and memory systems in the brain, which could account for sufferers having a reduced focus on happy memories.

read the full article.. medicalxpress.com/news/2016-10-depression-physical-source-potential-treatments.html


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Healthy mice born from first lab-grown eggs spark calls for debate on future use.

The birth of baby mice made from artificial eggs has prompted calls for a public debate on whether the same approach should ever be offered by fertility clinics. Nearly a dozen rodents were born after scientists created the early-stage mouse eggs from stem cells and nurtured them in the lab until they were mature enough to fertilise with mouse sperm. The team went on to make hundreds of embryos from the lab-grown eggs and implanted them into female mice, leading some to give birth to apparently healthy mouse pups.

read the full article.. www.theguardian.com/science/2016/oct/17/healthy-mice-born-from-lab-grown-eggs-spark-calls-for-debate-on-future-use


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YouthExtension vimeo channel updated.

There are some added videos on vimeo.com/youthextension ..on the topic of health — in English, French and Russian. I have only selected videos which are hard to find and/or in danger of being lost from public knowledge, thus in other languages which I also speak well (Spanish, Italian) there’s nothing to add currently — in other languages the videos of great value are mostly translations from English, French or Russian. All videos posted on YE vimeo channel are possible to download — usually there are three options to choose the video quality. That’s a better way – downloading first – than sometimes troublesome watching online. Use the opportunity today, because who knows about tomorrow.

vimeo.com/youthextension

A note: the YE youtube channel has no videos yet because I keep it for the time then I’ll be recording my own lectures, when there’s the right time for it.


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Big Sugar Is the New Big Tobacco.

The news for Big Sugar has not been all too sweet as of late. Just days ago, researchers published a study showing that Coca-Cola and PepsiCo are systematically undermining the scientific literature on the detrimental effects of sugar by sponsoring favorable studies under the guise of “charitable giving.” In addition, last month another study came out showing that the Sugar Association, the sugar industry’s trade association and lobbying arm, paid Harvard researchers in the 1960s to hide the impact of sugar on coronary health and shift the blame to fats.

Though these actions occurred in the 1960s, the cumulative negative impact on government health policy can be felt to this day. Both studies contribute to a growing body of literature and numerous disturbing examples telling us what many have suspected for quite some time: that the sugar industry is following the playbook of Big Tobacco in order to undermine public health policy in the pursuit of profits.

read the full article.. go.newsfusion.com/science-news/item/4464442


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Facebook blocking accounts.

Facebook had once again blocked my account, walking me through the trouble to reopen the account, forcibly change user name, reconnect automated post feed from WordPress and add another admin to the fb YE page in case the account associated with the page gets blocked again. It is not worth the time anymore — facebook isn’t the entire online world to get important messages out. Thus, I will still be relying on the automated WordPress YE post feed to facebook YE page as long as the system works, but not paying much attention to it anymore. YE fb groups will (also) be unattended. For facebook users: if you’re still interested in YE posts move your attention over to the youthextension.wordpress.com ..and subscribe to get new posts directly to your mailbox.


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Have you made an impact on society for a better life?

If not yet then now you have a chance! It is a duty of every intelligent person to use strong cryptography, so that governments won’t become tyrannical. You don’t need to worry about terrorism — you will not aid any potential or current terrorists. Governments themselves create them to have an excuse to take your liberties. Cryptography won’t provide potential terrorists with weapons of war — governments do. As your weapons to protect yourselves are taken away, your only true weapon is word of truth, protected by cryptography. If you don’t use cryptography you’re part of the problem in this world — you’re aiding governments to control the lives of average people, which they’re not meant to do. A good government must be a servant of people, to coordinate and achieve things that people in small groups cannot achieve, for the benefit of all. A good government has no business in your lives if you’re not a threat to the society. Using strong cryptography by ordinary people keeps governments minding their business, restraining authorities to given duties and not letting them to abuse their powers. Using strongest cryptography possible should be a moral duty of every intelligent person who cares about society.

Make an impact now.. learn AHC – Advanced Handwriting Cryptography.


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Portugal to levy sugar tax on soft drinks.

The announcement comes just three days after the World Health Organization urged countries to start taxing sugary drinks, pointing to evidence that price hikes can dramatically reduce consumption. Under Portugal’s plans, drinks with asugar content above 80 grammes per litre will be slapped with a tax of 16.46 euros per hectolitre. Drinks with less than 80 grammes of sugar per litre will pay a tax of 8.22 euros per hectolitre. The tax will raise the price of a standard 330 millilitre can of Coca-Cola, which contains 35 grammes of sugar, by 5.5 euro cents. The new tax will only apply to soft drinks. Sugary drinks based on milk or fruit juice will be spared.

read the full article.. medicalxpress.com/news/2016-10-portugal-levy-sugar-tax-soft.html


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Human Cell Atlas project aims to map the human body’s 35 trillion cells.

Aiming to decipher the types and properties of every cell, the project will attempt to work out exactly what we are made from and how illness develops. Labs around the world will create the most comprehensive map of the 35 trillion cells that make up the human body under plans put forward by researchers on Friday. The international effort aims to decipher the types and properties of every cell a person contains, whether healthy or diseased, in a bid to speed up discoveries in medical science. Named the Human Cell Atlas, the project amounts to the most concerted attempt yet to work out what we are made from and how illnesses develop when the building blocks of the body fail.

read the full article.. www.theguardian.com/science/2016/oct/14/human-cell-atlas-project-aims-to-map-the-human-bodys-35-trillion-cells


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Study finds knowingly taking placebo pills eases pain.

Conventional medical wisdom has long held that placebo effects depend on patients’ belief they are getting pharmacologically active medication. A paper published today in the journal Pain is the first to demonstrate that patients who knowingly took a placebo in conjunction with traditional treatment for lower back pain saw more improvement than those given traditional treatment alone.

“These findings turn our understanding of the placebo effect on its head,” said joint senior author Ted Kaptchuk, director of the Program for Placebo Studies and the Therapeutic Encounter at Beth Israel Deaconess Medical Center and an associate professor of medicine at Harvard Medical School. “This new research demonstrates that the placebo effect is not necessarily elicited by patients’ conscious expectation that they are getting an active medicine, as long thought.

read the full article.. medicalxpress.com/news/2016-10-knowingly-placebo-pills-eases-pain.html


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Why brain uses so much energy?

A researcher at IBM has uncovered what could be a start to these answers: a model for what the brain does at rest, when it’s not reading or thinking or cooking you breakfast. IBM neuroscientist James Kozloski calls it “the Grand Loop.”

“The brain consumes a great amount of energy doing nothing. It’s a great mystery of neuroscience,” Kozloski said. “You don’t spend that much energy on noise unless there’s a really good reason.”

Kozloski says about 90 percent of the energy consumed by the brain is unaccounted for, which is a considerable amount given that the brain takes 20 percent of the body’s total energy. He proposes that the brain is actually always looping signals through a series of pathways in the brain, made of neurons and tissue.

read the full article.. www.popsci.com/ibm-research-thinks-its-solved-brain


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Brain Implant Restores Sense Of Touch To Paralyzed Man.

For several years now, people have been able to control robotic arms using thoughts alone. But they have relied entirely on vision to know whether the arm is going in the right direction or grasping an object with the proper amount of force. That makes it very challenging to perform simple tasks like grasping a foam coffee cup without crushing it, McLoughlin says.

“Without sensory feedback, somebody would have to actually have to look at the prosthetic, look at the cup, start to close the hand, (and) visually see the cup is starting to deform,” he says.

Restoring Copeland’s sense of touch was a painstaking process, but the Pittsburgh team knew it was possible.

read the full article.. www.npr.org/sections/health-shots/2016/10/13/497716281/brain-implant-restores-sense-of-touch-to-paralyzed-man


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The Universe Is 10 Times More Vast Than We Thought.

Astronomers from the University of Nottingham conducted a new survey of the universe’s galaxy population and concluded that previous estimates lowballed the census by a factor of about 10. Using data from Hubble and telescopes around the world, as well as a new mathematical model, they estimate that there are ten times more galaxies in the observable universe than we thought; previous estimates put the number of galaxies in the universe at around 200 billion.

read the full article.. blogs.discovermagazine.com/d-brief/2016/10/13/the-universe-is-20-times-more-vast-than-we-thought/


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Posts of the blog not visible on every device? Rotate the screen!

Rotate tablet/cellphone 90 degrees if any issues with seeing posts!

Due to ever increasing number of different screen sizes of electronic devices some screens may show the sidebar first and the main content (posts) below that, if the automatic adjustment fails. The blog comes in three different, automatically selected forms: for PC, for tablet and for cellphone. Depending on browser settings some devices may get confused in displaying the correct format of the blog. Simply rotate the screen 90 degrees and you should see the blog better. If that won’t do then modify settings of your browser or download a better one — not all developers are delivering good enough apps.


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Antidepressants during pregnancy associated with childhood language disorders.

Mothers who purchased antidepressants at least twice during pregnancy had a 37-percent increased risk of speech and/or language disorders among their offspring compared to mothers with depression and other psychiatric disorders who were not treated with antidepressants, according to new research. Results by scientists at Columbia University’s Mailman School of Public Health and Columbia University Medical Center will be published online in JAMA Psychiatry.

read the full article.. medicalxpress.com/news/2016-10-antidepressants-pregnancy-childhood-language-disorders.html


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Running triggers brain repair and extends life in mouse model.

Breaking research demonstrates that running in brain-damaged mice triggers the production of a molecule that repairs brain tissue and extends their lifespan. The investigators hope that the findings could lead to innovative treatments for certain neurodegenerative disorders.

read the article.. www.medicalnewstoday.com/articles/313399.php


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Mars-bound astronauts face chronic dementia risk from galactic cosmic ray exposure.

Will astronauts traveling to Mars remember much of it? That’s the question concerning scientists probing a phenomenon called “space brain.” Scientists have found that exposure to highly energetic charged particles — much like those found in the galactic cosmic rays that will bombard astronauts during extended spaceflights — causes significant long-term brain damage in test rodents, resulting in cognitive impairments and dementia.

read the full article.. www.sciencedaily.com/releases/2016/10/161010052832.htm


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Cell protein offers new hope in fighting the effects of aging.

A protein found within the powerhouse of a cell could be the key to holding back the march of time, research by scientists at The University of Nottingham has shown.

/…/ The work, led by Dr Lisa Chakrabarti and PhD student Amelia Pollard in the University’s School of Veterinary Medicine and Science, has centred on a family of proteins called carbonic anhydrase found within mitochondria—the cells’ ‘batteries’ which convert the oxygen we breathe into the energy (ATP) needed to power our body.

/…/ Using a specialist process called 2D gel electrophoresis, the scientists separated out all the proteins found within the mitochondria of brain cells and muscle cells from normal young brains and normal middle-aged brains and compared the two samples. They found that the carbonic anhydrase was found in greater quantity and was more active in the samples of the middle-aged brain. Significantly, this increase was also reflected in samples from young brains suffering from early degeneration, suggesting that the increase is detrimental.

read the full article.. medicalxpress.com/news/2016-10-cell-protein-effects-aging.html


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Scientists Connect Neurons in the Lab for the First Time. (video)

Injuries to the central nervous system — the brain and spinal cord — are particularly devastating because the body doesn’t regenerate neurons to repair connections between vital circuits and restore function. In other words, the damage is permanent or even fatal.

/…/ Working with rat neurons grown in a petri dish in the laboratory, the team artificially connected two neurons using an atomic force microscope and tiny, polystyrene spheres. Though the work is an early proof-of-concept, it could lay the foundation for novel surgeries and therapies for people with brain and spinal damage.

/…/ Researchers used a specialized microprobe to grab on to an axon, the part of a neuron that connects it to others in the brain, and stretch it across the dish to connect it to another neuron. Their microprobe takes advantage of minuscule forces between objects at the atomic level to grasp the polystyrene spheres, which in turn hold the axon.

read the full article.. blogs.discovermagazine.com/d-brief/2016/02/09/scientists-connect-neurons-in-the-lab-for-the-first-time/


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Brain modulyzer provides interactive window into the brain.

For the first time, a new tool developed at the Department of Energy’s (DOE’s) Lawrence Berkeley National Laboratory (Berkeley Lab) allows researchers to interactively explore the hierarchical processes that happen in the brain when it is resting or performing tasks.

/…/ Created in conjunction with computer scientists at University of California, Davis (UC Davis) and with input from neuroscientists at UC San Francisco (UCSF), the software, called Brain Modulyzer, combines multiple coordinated views of functional magnetic resonance imaging (fMRI) data–like heat maps, node link diagrams and anatomical views–to provide context for brain connectivity data.

read the full article.. www.eurekalert.org/pub_releases/2016-10/dbnl-bmp100716.php


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Newly discovered gut organism protects mice from bacterial infections.

While bacteria are often stars of the gut microbiome, emerging research depicts a more complex picture, where microorganisms from different kingdoms of life are actively working together or fighting against one another. In a study published October 6 in Cell, scientists reveal one example: a newly discovered protist that protects its host mice from intestinal bacterial infections.

/…/ The fight against pathogens determined the survival of the human species, and those with stronger immune systems are the ones who survived. It is likely that the microbiome is a big part of the evolutionary process. Thus, identifying those commensals that confer immune strength in exposed communities should help identify novel therapeutics.

read the article.. medicalxpress.com/news/2016-10-newly-gut-mice-bacterial-infections.html


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Brain cell ‘executioner’ identified.

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer’s. Now, researchers at Johns Hopkins say they have pinpointed the protein at the end of that chain of events, one that delivers the fatal strike by carving up a cell’s DNA. The find, they say, potentially opens up a new avenue for the development of drugs to prevent, stop or weaken the process.

/…/ “I can’t overemphasize what an important form of cell death it is; it plays a role in almost all forms of cellular injury,” Ted Dawson says. His and Valina Dawson’s research groups have spent years delineating each of the links in the parthanatos chain of events and the roles of the proteins involved.

read the article.. medicalxpress.com/news/2016-10-brain-cell-executioner-common-culprit.html


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How much time/work does it take to create your own code?

An important information has been left out from the ‘synopsis‘ post: How much time/work does it take to create your own code?

ap800ok-white

Using the encryption technique, described in the AHC book in detail, one could build a personal encoding method in matter of 10 minutes (basic code), about a week (medium level code) or approximately a month (the highest level code), depending on needs for safety, which can then be used during entire lifetime. You don’t need to spend 30 years to achieve the same results — the development of and perfecting the encryption technique took so long time, my time, now the art of writing in the unbreakable code is described and available for use by others in quite a simple way. This is not a process of creating your personal language, it’s encoding the language(s) you already know the way others can’t understand. Only those having the custom keys will have access to the encoded information.

With Best Wishes, A. K.

Reference to the post: Synopsis of the AHC book.


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ahc-script-long-sample-edge-emboss-sketch

New method to detect aging cells, and aid rejuvenation therapies, developed by researchers.

Scientists have discovered a new way to look for aging cells across a wide range of biological materials; the new method will boost understanding of cellular development and aging as well as the causes of diverse diseases.

/…/ Cellular senescence is a fundamental biological process involved in every day embryonic and adult life, both good — for normal human development — and, more importantly to researchers, dangerous by triggering disease conditions. Up to now available senescence detecting biomarkers have very limited and burdensome application. Therefore, a more effective, precise and easy-to-use biomarker would have considerable benefits for research and clinical practice.

“The method we have developed provides unprecedented advantages over any other available senescence detection products — it is straight-forward, sensitive, specific and widely applicable, even by non-experienced users,” said Professor Townsend. /…/ “By the better identification — and subsequently elimination of — senescent cells, tissues can be rejuvenated and the health span extended.”

read the full article.. www.sciencedaily.com/releases/2016/10/161005084033.htm


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How the brain consolidates memories during sleep.

Researchers in the group of Prof Dr Nikolai Axmacher at the Ruhr-Universität Bochum (RUB) have studied which brain processes consolidate memories during sleep. They found clear parallels to findings from experimental animal studies. The RUB’s science magazine Rubin reports on the work of the Bochum neuropsychologists.

/…/ Ripples are a specific kind of brain activity. A group of interconnected nerve cells sends out signals at high frequency for a short period of time. In the EEG they appear as a characteristic wave form. One theory is: After a ripple event, a brain area is more receptive for long-term storage of reactivated information. /…/ “Individual stimuli, in our case landscape images, are reactivated during sleep, and the ripples seem to actively maintain this reactivation,” explains Nikolai Axmacher. However, the researchers found this enhancement mechanism only for the reactivation of those images that were recalled during the final test.

read the article.. www.sciencedaily.com/releases/2016/10/161005083700.htm


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Limit to human life may be 115 (ish). [say some, others disagree]

Human life spans may be limited to a maximum of about 115 years, claim US scientists. Their conclusions, published in the journal Nature, were made by analysing decades of data on human longevity. They said a rare few may live longer, but the odds were so poor you’d have to scour 10,000 planet Earths to find just one 125-year-old. But while some scientists have praised the study, others have labelled it a dismal travesty.

/…/ The 115-year claim is too much for Prof James Vaupel, the director of the Max Planck Institute for Demographic Research. He described the study as a dismal travesty and said scientists had in the past claimed the limit was 65, 85 and 105 only to be proven wrong over and over again.

read the full article.. www.bbc.co.uk/news/health-37552116


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The science, drugs and tech pushing our brains to new limits.

A recent explosion of neuroscience techniques is driving substantial advances in our understanding of the brain. Combined with developments in engineering, machine learning and computing this flowering has helped us enhance our cognitive abilities and potential. In fact, new research into the extraordinary machine in our skulls is helping us keep pace with the rapid rise of artificial intelligence.

Exciting new advances are everywhere, but worth putting front and centre are findings made in the relatively new area of social neuroscience. Research by Molly Crockett at Oxford University has demonstrated how we might influence the social brain and examine the effects of neurotransmitters, such as serotonin, and hormones, such as oxytocin, on social cognition and social interactions. This includes the most fundamental aspects of our daily lives: trust, punishment, moral judgement, conformity and empathy.

read the article.. theconversation.com/the-science-drugs-and-tech-pushing-our-brains-to-new-limits-65281


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Cells’ garbage disposal may hold key to healthier life.

Autophagy, the little-understood method by which human cells dispose of harmful waste and unwelcome intruders, may one day be central to therapies for longer, healthier living, experts said.

Japanese cell biologist Yoshinori Ohsumi was awarded the 2016 Nobel Medicine Prize Monday for discovering genes involved in autophagy, a non-stop housecleaning process that keeps cells healthy, and is thought to spur ageing and disease when disrupted.

read the article.. medicalxpress.com/news/2016-10-cells-garbage-disposal-key-healthier.html


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How humans evolved to harm each other.

To find out how humans compare to other mammals, and how our history of shedding each other’s blood came to be, José María Gómez at the University of Granada and his colleagues used phylogenetic analysis and data from over four million deaths. They quantified the level of lethal violence in 1,024 mammal species from 137 taxonomic families and in about 600 human populations, ranging from about 50,000 years ago to the present.

read the full article.. www.popsci.com/new-massive-study-shows-how-humans-evolved-to-hurt-each-other


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Where you live shapes your immune system more than your genes.

Like fingerprints, immune systems vary from person to person. And although we all inherit a unique set of genes that help us respond to infections, recent studies have found that our history and environment—like where and with whom we live—are responsible for 60% to 80% of the differences between individual immune systems, while genetics account for the rest. In a Review published September 29 in Trends in Immunology, three immunologists discuss the emerging science of what shapes our immune systems and how it might be applied.

read the full article.. medicalxpress.com/news/2016-10-immune-genes.html


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Found: a gene that prevents elephants from getting cancer.

Logically, elephants should get cancer much more than humans do—elephants have 100 times more cells than we do and live just about as long, providing ample opportunity for cancer-causing mutations to occur. But in fact they have less cancer; an analysis of hundreds of zoo deaths found that only five percent of elephants die of cancer, whereas 11 to 25 percent of humans do, according to the New York Times. Scientists hypothesize that, in order to get so large and biologically complex, elephants’ bodies must have evolved a way to suppress cancer. But they weren’t sure quite how they kept the cancer at bay.

read the full article.. www.popsci.com/this-gene-prevents-elephants-from-getting-cancer


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Scientists uncover how a fluctuating brain network may make us better thinkers.

For the past 100 years, scientists have understood that different areas of the brain serve unique purposes. Only recently have they realized that the organization isn’t static. Rather than having strictly defined routes of communication between different areas, the level of coordination between different parts of the brain seems to ebb and flow.

Now, by analyzing the brains of a large number of people at rest or carrying outcomplex tasks, researchers at Stanford University have learned that the integration between those brain regions also fluctuates. When the brain is more integrated people do better on complex tasks. The research was published inNeuron.

read the full article.. medicalxpress.com/news/2016-09-scientists-uncover-fluctuating-brain-network.html


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Healthy lifestyle in old age shortens end-of-life disability.

Leading a healthy lifestyle not only extends one’s lifespan, but it also shortens the time that is spent disabled—a finding that had previously eluded public health scientists and demonstrates the value of investing in healthy lifestyle promotion, even among the elderly.

An analysis of a quarter century of data by scientists at the University of Pittsburgh Graduate School of Public Health and their colleagues nationwide revealed that older adults with the healthiest lifestyles could expect to spend about 1.7 fewer years disabled at the end of their lives, compared to their unhealthiest counterparts. The study results are online and scheduled for the October issue of the Journal of the American Geriatrics Society.

read the full article.. medicalxpress.com/news/2016-09-healthy-lifestyle-age-shortens-end-of-life.html


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What parts of the brain make our personalities so unique?

Since everyone is different in their own way, psychologists have debated how to characterise personality. The most popular approach has so far been to use five dimensions: openness to experience (curious or cautious), conscientiousness (organised or careless), extraversion (outgoing or solitary), agreeableness (friendly or detached) and neuroticism (nervous or secure).

A self-report questionnaire is often used to give a score to each dimension, which then describes someone’s personality. These descriptions have been used to understand normal and abnormal behaviour, and to predict work success, academic achievementand interpersonal relationships.

read the full article.. medicalxpress.com/news/2016-09-brain-personalities-unique.html


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